Which gauge would be best for starting up a layout for model railroading?

Question by eventhorizon: Which gauge would be best for starting up a layout for model railroading?
Space is not an issue. I’m hoping for one with the greatest variety of trains, cars, and accesories. And can tracks and trains(motors) from different manufactures be used together?

Best answer:

Answer by greencreeper
HO, although that’s really a scale, not a gauge.

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